Objective:An
epidemiological investigation was carried out in school X in Jinan, Shandong
Province,China, to identify
the cause, epidemiology,and etiological characteristics of a febrile respiratory disease
outbreak; and therefore to control the dissemination. Methods:Both field epidemiological
investigations and laboratory examinations were carried out. Results: Forty cases were identified,
in which 38 cases were students and two were teachers.Clinical manifestations included
fever, coughing, headache, and sore throat. A total of 21 pharyngeal swab
specimens were collected and 18 tested positive for adenovirus. The
adenovirus hexon gene was sequenced in three of the 18 positive specimens and
the results showed a 100% homology with the standard
HAdV-55 HEXO. Conclusions: The
outbreak originated from an adenovirus-infected student, who spread the
pathogen to her classmates and teacher. The teacher then further disseminated
the disease within the school which led to 40 febrile respiratory infections.
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