%0 Journal Article
%T Investigation of an Adenovirus-Induced Respiratory Disease Outbreak
%A Xingyi Geng
%A Ji Zhang
%A Guoliang Yang
%J Advances in Infectious Diseases
%P 257-262
%@ 2164-2656
%D 2013
%I Scientific Research Publishing
%R 10.4236/aid.2013.34039
%X <p class=\"MsoNormal\" style=\"text-align:justify;\">
	<b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Objective:</span></b><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;\">An
epidemiological investigation was carried out in school X in Jinan, Shandong
Province,</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;\">China, to identify
the cause, epidemiology,</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">and etiological characteristics of a febrile respiratory disease
outbreak; and therefore to control the dissemination. </span><b><span style=\"font-family:Verdana;\">Methods:</span></b> <span style=\"font-family:Verdana;\">Both field epidemiological
investigations and laboratory examinations were carried out. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> Forty cases were identified,
in which 38 cases were students and two were teachers.</span></span><span lang=\"EN-US\"> </span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">Clinical manifestations included
fever, coughing, headache, and sore throat. A total of 21 pharyngeal swab
specimens were collected and 18&nbsp;</span><span style=\"font-family:Verdana;\">tested positive for adenovirus. The
adenovirus hexon gene was sequenced in three of the 18 positive specimens and
the results&nbsp;</span><span style=\"font-family:Verdana;\">showed a 100% homology with the standard
HAdV-55 HEXO. </span><b><span style=\"font-family:Verdana;\">Conclusions:</span></b><span style=\"font-family:Verdana;\"> The
outbreak originated from an adenovirus-infected student, who spread the
pathogen to her classmates and teacher. The teacher then further disseminated
the disease within the school which led to 40 febrile respiratory infections.</span></span><span lang=\"EN-US\"><o:p></o:p></span>
</p>
<p class=\"MsoNormal\" style=\"text-align:justify;\">
	<span lang=\"EN-US\" style=\"font-family:Verdana;\">&nbsp;</span>
</p>
%K Epidemiology
%K Research Methods
%K Laboratory Examination
%K Adenovirus
%K Respiratory Disease
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=40478