Background: Chronic paronychia is a chronic
inflammatory reaction of the proximal and lateral nail folds of multifactorial
in etiology like irritant, bacterial and monilial causes. But housewife work is
a major cause of chronic paronychia. Objective: To assess the efficacy
and prophylactic effects of Vaseline by occlusion of nail folds in comparison
with nystatin ointment and fucidic acid in treatment of housewife chronic
paronychia. Patients and Methods: This double, blinded, comparative
therapeutic, clinical trial is conducted at the Department of Dermatology-Baghdad Teaching Hospital from
May 2010 to May 2011. Eighty female housewife patients with chronic paronychia
were included in this trial. They were divided into three groups according to
the following therapeutic model: Group A treated by Vaseline consisted
of 40 patients;Group
B and Group C treated by nystatin ointment, fucidic acid ointment
respectively and each group consisted of 20 patients. All demographic points
related to the disease were recorded from all patients. Invented score system
was applied to assess the severity of disease and the response to therapy. Patients
had used therapy twice daily on the proximal and lateral nail folds. Treatment
duration was 12 weeks. Results: Group A (Vaseline): The recovery
rate after 12 weeks of treatment was 26(65%) patients, while there was no
recovery in 14(35%)
patients. Group B (Nystatin ointment): The recovery rate after 12
weeks was 13 (65%) cases
References
[1]
K. E. Sharquie and S. I. Al-Omran, “Occupational Housewife Dermatosis,” Diploma Dissertation, University of Baghdad, Baghdad, 1988.
[2]
K. E. Sharquie, S. M. Al-Salloum and R. N. Al-Saadi, “Microbiology of Chronic Paronychia in Iraqi Housewives,” Journal of Pan Arab League of Dermatologists, Vol. 1, No. 2, 1990, pp. 17-23.
[3]
I. Brook, “Paronychia: A Mixed Infection: Microbiology and Management,” The Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand, Vol. 18, No. 3, 1993, pp. 385-359.
[4]
C. R. Daniel, M. P. Daniel, C. M. Daniel, S. Sullivans and G. Ellis, “Chronic Paronychia and Onycholysis: A Thirteen Year Experience,” Cutis, Vol. 85, No. 6, 1996, pp. 397-401.
[5]
D. A. R. De Berker and E. R. Baran, “Disorders of Nails,” In: T. Burns, S. Breathnach, N. Cox and C. Griffiths, Eds., Rooks Textbook of Dermatology, 6th Edition, Blackwell Scientific Publications, Melblorne, 1998, p. 65.
[6]
C. Grover, B. S. N. Reddy and K. U. Chaturvedi, “Nail Biopsy: An Assessment of Indications and Outcome,” Dermatologic Surgery, Vol. 31, No. 2, 2005, pp. 190-194.
http://dx.doi.org/10.1111/j. 1524-4725.2005.31042
[7]
E. S. M. Wong, R. J. Hay, Y. M. Clayton and W. C. Noble, “Comparison of the Therapeutic Effect of Ketoconazole Tablets and Econazole Lotion in the Treatment of Chronic Paronychia,” Clinical and Experimental Dermatology, Vol. 9, No. 5, 1984, pp. 489-496.
http://dx.doi.org/10.1111/j.1365-2230.1984.tb00843.x
[8]
M. A. A. Al-Nuaimi, “Chronic Paronychia: The Fungal and Bacteriological Etiology in Iraqi Patients,” MS Thesis, University of Baghdad, Baghdad, 2001.
