%0 Journal Article
%T Treatment of Chronic Paronychia: A Double Blind Comparative Clinical Trial Using Singly Vaseline,  Nystatin and Fucidic Acid Ointment
%A Khalifa E. Sharquie
%A Adil A. Noaimi
%A Sunbul A. Galib
%J Journal of Cosmetics, Dermatological Sciences and Applications
%P 250-255
%@ 2161-4512
%D 2013
%I Scientific Research Publishing
%R 10.4236/jcdsa.2013.34038
%X <p>
	<b><span style=\"font-family:Verdana;\">Background: </span></b><span><span style=\"font-family:Verdana;\">Chronic paronychia is a chronic
inflammatory reaction of the proximal and lateral nail folds of multifactorial
in etiology like irritant, bacterial and monilial causes. But housewife work is
a major cause of chronic paronychia. </span><b><span style=\"font-family:Verdana;\">Objective: </span></b><span style=\"font-family:Verdana;\">To assess the efficacy
and prophylactic effects of Vaseline by occlusion of nail folds in comparison
with nystatin ointment and fucidic acid in treatment of housewife chronic
paronychia. </span><b><span style=\"font-family:Verdana;\">Patients and Methods: </span></b><span style=\"font-family:Verdana;\">This double, blinded, comparative
therapeutic, clinical trial </span></span><span style=\"font-family:Verdana;\">is </span><span><span style=\"font-family:Verdana;\">conducted at the Department of Dermatology-Baghdad Teaching Hospital from
May 2010 to May 2011. Eighty female housewife patients with chronic paronychia
were included in this trial. They were divided into three groups according to
the following therapeutic model: </span><b><i><span style=\"font-family:Verdana;\">Group A</span></i></b><span style=\"font-family:Verdana;\"> treated by Vaseline consisted
of 40 patients</span></span><span style=\"font-family:Verdana;\">;</span><span> <b><i><span style=\"font-family:Verdana;\">Group
B and Group C </span></i></b><span style=\"font-family:Verdana;\">treated by nystatin ointment, fucidic acid ointment
respectively and each group consisted of 20 patients. All demographic points
related to the disease were recorded from all patients. Invented score system
was applied to assess the severity of disease and the response to therapy. Patients
had used therapy twice daily on the proximal and lateral nail folds. Treatment
duration was 12 weeks. </span><b><span style=\"font-family:Verdana;\">Results: </span><i><span style=\"font-family:Verdana;\">Group A </span></i><span style=\"font-family:Verdana;\">(Vaseline): </span></b><span style=\"font-family:Verdana;\">The recovery
rate after 12 weeks of treatment was 26</span></span><span> </span><span style=\"font-family:Verdana;\">(65%) patients, while there was no
recovery in 14</span><span> </span><span><span style=\"font-family:Verdana;\">(35%)
patients. </span><b><i><span style=\"font-family:Verdana;\">Group B </span></i><span style=\"font-family:Verdana;\">(Nystatin ointment): </span></b><span style=\"font-family:Verdana;\">The recovery rate after 12
weeks was 13 (65%) cases
%K Housewife
%K Paronychia
%K Vaseline
%K Occlusive Therapy
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=40360