Conclusion: Early-stage detection of temporal bone carcinoma improves the survival rate. When
detected at an advanced
stage, predicted prognosis is poor even with a combination of surgery,
radiotherapy and chemotherapy. Objectives: We
evaluated treatment strategies and survival rates in cases of carcinomas of the external and
middle ear. Method: Retrospective review
of patients treated at Ehime University Hospital during the 32 years from 1977
to 2008. Subjects were 41 patients, consisting of 21 men and 20 women with a
mean age of 63.2 years. Modified Pittsburgh staging system: stage I in 11 cases
(27%), stage II in 4 (10%), stage III in 6 (15%) and stage IV in 20 (49%).
Histopathology: squamous
cell carcinoma (SCC) in 35 cases, adenoid cystic carcinoma (ACC) in 3, and
adenocarcinoma (AC) in 3. Thirty-eight patients were treated by surgery.
Radiation was added postoperatively in 23 patients. Three patients were treated
by chemoradiotherapy. Results:The survival rate of carcinomas
detected at an advanced stage was poor with a disease-specific
5-year survival rate of 100% in early-stage disease (stage I and II) versus
20.8% in stage III and 27.5% in stage IV disease, irrespective of
histopathology of the tumor.
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