%0 Journal Article
%T Survival in Primary Carcinoma of the External and Middle Ear Is Strongly Dependent on Stage at Diagnosi
%A Toru Ugumori
%A Jun Hyodo
%A Naohito Hato
%A Kiyofumi Gyo
%J International Journal of Otolaryngology and Head & Neck Surgery
%P 221-227
%@ 2168-5460
%D 2013
%I Scientific Research Publishing
%R 10.4236/ijohns.2013.26046
%X <span style=\"font-size:10pt;font-family:Verdana;\">Conclusion:</span><span style=\"font-size:10pt;font-family:Verdana;\"> Early-stage detection of temporal bone carcinoma improves </span><span style=\"font-size:10pt;font-family:Verdana;\">the </span><span style=\"font-size:10pt;font-family:Verdana;\">survival rate. When
detected at an ad</span><span style=\"font-size:10.0pt;font-family:&quot;\"><span style=\"font-family:Verdana;\">vanced
stage, predicted prognosis is poor even with a combination of surgery,
radiotherapy and chemotherapy. </span><span style=\"font-family:Verdana;\">Objec</span></span><span style=\"font-size:10pt;font-family:Verdana;\">tives:</span><span style=\"font-size:10pt;font-family:Verdana;\"> We
evaluated treatment strategies and survival rates in cases </span><span style=\"font-size:10pt;font-family:Verdana;\">of </span><span style=\"font-size:10pt;font-family:Verdana;\">carcinoma</span><span style=\"font-size:10pt;font-family:Verdana;\">s</span><span style=\"font-size:10.0pt;font-family:&quot;\"><span style=\"font-family:Verdana;\"> of the external and
middle ear. </span><span style=\"font-family:Verdana;\">Method:</span><span style=\"font-family:Verdana;\"> Retrospective review
of patients treated at Ehime University Hospital during the 32 years from 1977
to 2008. Subjects were 41 patients, consisting of 21 men and 20 women with a
mean age of 63.2 years. Modified Pittsburgh staging system: stage I in 11 cases
(27%), stage II in 4 (10%), stage III in 6 (15%) and stage IV in 20 (49%).
Histopa</span></span><span style=\"font-size:10.0pt;font-family:&quot;\"><span style=\"font-family:Verdana;\">thology: squamous
cell carcinoma (SCC) in 35 cases, adenoid cystic carcinoma (ACC) in 3, and
adenocarcinoma (AC) in 3. Thirty-eight patients were treated by surgery.
Radiation was added postoperatively in 23 patients. Three patients were treated
by </span><span><span style=\"font-family:Verdana;\">chemoradiotherapy. </span><span style=\"font-family:Verdana;\">Results:</span> </span></span><span style=\"font-size:10pt;font-family:Verdana;\">The s</span><span style=\"font-size:10pt;font-family:Verdana;\">urvival rate of carcinomas
detected at an advanced stage was poor with a dis</span><span style=\"font-size:10pt;font-family:Verdana;\">ease-specific
5-year survival rate of 100% in early-stage disease (stage I and II) versus
20.8% in stage III and 27.5% in stage IV disease, irrespective of
histopathology of the tumor.</span>
%K Survival
%K Staging
%K External Auditory Canal
%K Middle Ear
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=39295