Objective:The traditional approach
for acid base interpretation is based on Handerson-Hasselbalch formula and includesBase
Excess (BE),bicarbonate (HCO3),albumin corrected
anion gap.The Physicochemical approach is centered on the Carbon Dioxide
tension (PCO2), the strong ion difference (SID),strong ion gap (SIG)= SID
apparent-SID effective and totally weak acids (Atot).The study aims to
compare between the traditional approach and the physicochemical approach in
acid base disorder interpretation.Design: Prospective
observational study in an adult Intensive Care Unit (ICU) recruiting six
hundred and sixty one patients. Methods: Arterial blood samples were analyzed to measure pH, PaCO2
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