%0 Journal Article
%T Comparative Study between Traditional Approach and Physico-Chemical Approach in Acid Base Disorders Interpretation in Critically Ill Patients
%A Atef Redwan
%A Rainer Gatz
%A Naglaa Hassan
%A Heba Matter
%A Adel Hammodi
%A Adel Attia
%J Open Journal of Respiratory Diseases
%P 143-149
%@ 2163-9418
%D 2013
%I Scientific Research Publishing
%R 10.4236/ojrd.2013.34022
%X <p class=\"MsoNormal\">
	<b><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">Objective:</span></b><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">The traditional approach
for acid base interpretation is based on Handerson-Hasselbalch formula and includes</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">Base
Excess (BE),</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\"><span style=\"font-family:Verdana;font-size:10px;\">bicarbonate (HCO</span><sub><span style=\"font-family:Verdana;font-size:10px;\">3</span></sub><span style=\"font-family:Verdana;font-size:10px;\">),</span></span><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">albumin corrected
anion gap.</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\"><span style=\"font-family:Verdana;font-size:10px;\">The Physicochemical approach is centered on the Carbon Dioxide
tension (PCO</span><sub><span style=\"font-family:Verdana;font-size:10px;\">2</span></sub><span style=\"font-family:Verdana;font-size:10px;\">), the strong ion difference (SID)</span></span><span lang=\"NL\" style=\"font-family:Verdana;font-size:10px;\">,</span><span lang=\"NL\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">strong ion gap (SIG)</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">= SID
apparent-SID effective and total</span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">ly</span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\"> weak acids (Atot).</span><span lang=\"EN-US\"> </span><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">The study aims to
compare between the traditional approach and the physicochemical approach in
acid base disorder interpretation.</span><span lang=\"EN-US\"> </span><b><span lang=\"EN-US\" style=\"font-family:Verdana;font-size:10px;\">Design:</span></b><span lang=\"EN-US\"><span style=\"font-family:Verdana;font-size:10px;\"> Prospective
observational study in an adult Intensive Care Unit (ICU) recruiting six
hundred and sixty one patients. </span><b><span style=\"font-family:Verdana;font-size:10px;\">Methods</span></b><b><span style=\"font-family:Verdana;font-size:10px;\">:</span></b><span style=\"font-family:Verdana;font-size:10px;\"> Arterial blood samples were analyzed to measure pH, PaCO</span><sub><span style=\"font-family:Verdana;font-size:10px;\">2</span></sub><span
%K Anion Gap
%K Base Excess
%K Bicarbonate
%K Strong Ion Gap
%K Total Weak Acids
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=38097