Purpose: To evaluate planning quality and dosimetric differences of
clinically deliverable Intensity-modulated Radiation Therapy lung
plans generated from Tomotherapy, Pinnacle3, and RayStationTM treatment planning systems. Method and
Materials: Ten patients diagnosed with non-small-cell lung carcinoma
(NSCLC) previously treated with plans on Pinnacle using Direct Machine
Parameter Optimization were randomly selected and re-planned with Tomotherapy
dose volume constraints and same beam geometry with RayStation Multi Criteria
Optimization (MCO) equivalent uniform dose (EUD) or dose volume
constraints, respectively. Prescription
was established as 60 Gy to cover > 95% of PTV. Planning outcomes such as D95 (95% of volume of PTV receiving the prescribed dose), D5, D33, mean heart and lung doses, V20 (volume of lung receiving 20
Gy), and max cord dose of 1cm3 were evaluated according to our departmental clinical protocols. Conformity
index (CI = PTV / prescription isodose volume) and homogeneity index (HI = D5/D95)
were also reported simultaneously. All plans were successfully
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