%0 Journal Article
%T Planning and Dosimetric Comparisons of IMRT Lung Cancers with Three Advanced Optimization Algorithms
%A Yie Chen
%A Jie Qu
%A Jack Yang
%A Mitch Weiss
%A Sang Sim
%A Xiongfei Liao
%J International Journal of Medical Physics,Clinical Engineering and Radiation Oncology
%P 52-60
%@ 2168-5444
%D 2013
%I Scientific Research Publishing
%R 10.4236/ijmpcero.2013.22008
%X <p class=\"MsoNormal\">
	<b><span lang=\"EN-US\" style=\"font-family:Verdana;\">Purpose</span></b><span lang=\"EN-US\" style=\"font-family:Verdana;\">: To evaluate planning quality and dosimetric differences of
clinically deliverable Intensity-modulated Radi</span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">ation Therapy lung
plans generated from Tomotherapy, Pinnacle</span><sup><span style=\"font-family:Verdana;\">3</span></sup><span style=\"font-family:Verdana;\">, and RayStation<sup>TM</sup> treatment planning systems. </span><b><span style=\"font-family:Verdana;\">Method and
Materials:</span></b><span style=\"font-family:Verdana;\"> Ten patients diagnosed with non-small-cell lung carcinoma
(NSCLC) previously treated with plans on Pinnacle using Direct Machine
Parameter Optimization were randomly selected and re-planned with Tomo</span></span><span lang=\"EN-US\" style=\"font-family:Verdana;\">therapy
dose volume constraints and same beam geometry with RayStation Multi Criteria
Optimization (MCO) equiva</span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">lent uniform dose (EUD) or dose volume
constraints, respectively.&nbsp; Prescription
was established as 60 Gy to cover &gt; 95% of PTV. Planning outcomes such as D</span><sub><span style=\"font-family:Verdana;\">95 </span></sub><span style=\"font-family:Verdana;\">(95% of volume of PTV receiving the prescribed dose), D</span><sub><span style=\"font-family:Verdana;\">5, </span></sub><span style=\"font-family:Verdana;\">D</span><sub><span style=\"font-family:Verdana;\">33, </span></sub><span style=\"font-family:Verdana;\">mean heart and lung doses, V</span><sub><span style=\"font-family:Verdana;\">20</span></sub><span style=\"font-family:Verdana;\"> (volume of lung receiving 20
Gy), and max cord dose of </span><st1:chmetcnv unitname=\"cm\" sourcevalue=\"1\" hasspace=\"False\" negative=\"False\" numbertype=\"1\" tcsc=\"0\" w:st=\"on\"><span style=\"font-family:Verdana;\">1cm</span></st1:chmetcnv><sup><span style=\"font-family:Verdana;\">3</span></sup><span style=\"font-family:Verdana;\"> were evaluated according to our de</span></span><span lang=\"EN-US\"><span style=\"font-family:Verdana;\">partmental clinical protocols. Conformity
index (CI = PTV / prescription isodose volume) and homogeneity index (HI = D</span><sub><span style=\"font-family:Verdana;\">5</span></sub><span style=\"font-family:Verdana;\">/D</span><sub><span style=\"font-family:Verdana;\">95</span></sub><span style=\"font-family:Verdana;\">)
were also reported simultaneously. All plans were successfully
%K MCO
%K DMPO
%K Tomotherapy
%K Lung IMRT
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=31813