RELEASE STUDIES OF KETOCONAZOLE NIOSOME FORMULATION

Antifungal drug ketoconazole was encapsulated in niosome for topical application .Ketoconazole niosome were prepared by thin film hydration method technique using surfactant, cholesterol, dicetyl phosphate & drug mixture in different weight ratios. The prepared niosomes were characterized by various physicochemical parameters & evaluation of release studies of entrapped ketoconazole in niosomes were carried out by UV Visible spectrophotometric method.