Invitro Effects of Our Spring Water on the Solubility of Uric Acid Stones: A Pilot Study

Aim: The aim of this study was to evaluate the influence of our spring water on urinary analytes and stone samples in (patient with) uric acid stone. Material and Methods: Twenty patients with uric acid stones underwent a nutritional and metabolic evaluation at baseline and after a controlled diet including our spring water. Stone samples were also left in the usual water and in the spring water. The weights of stones were measured before and 7 days after incubation. Results: In patients who drank spring water, there was a tendency for the mean urine pH to increase, the change was significant statistically. On the other hand, urine citrate excretion significantly also increased in these patients (p<0.005). The differences between initial and end-dry weights of stone examples were significant statistically (p<0.05). Conclusion: The results of our pilot study may help us to reduce uric acid stone formation and recurrence with the alkaline spring waters.