%0 Journal Article %T Invitro Effects of Our Spring Water on the Solubility of Uric Acid Stones: A Pilot Study %A Mustafa Ho£¿can %A Cem Dilmen %A Mehmet Ekinci %A S£¿tk£¿ Orak %J Journal of Clinical and Analytical Medicine %D 2010 %I Derman Medical Publishing %R 10.4328 %X Aim: The aim of this study was to evaluate the influence of our spring water on urinary analytes and stone samples in (patient with) uric acid stone. Material and Methods: Twenty patients with uric acid stones underwent a nutritional and metabolic evaluation at baseline and after a controlled diet including our spring water. Stone samples were also left in the usual water and in the spring water. The weights of stones were measured before and 7 days after incubation. Results: In patients who drank spring water, there was a tendency for the mean urine pH to increase, the change was significant statistically. On the other hand, urine citrate excretion significantly also increased in these patients (p<0.005). The differences between initial and end-dry weights of stone examples were significant statistically (p<0.05). Conclusion: The results of our pilot study may help us to reduce uric acid stone formation and recurrence with the alkaline spring waters. %K Uric Acid Stone %K Solubility of Stones %K Spring Water %U http://www.jcam.com.tr/files/64-1079-4-PB.pdf