TO ESTABLISH THE EFFECT OF GINGER-JUICE ZINGIBER OFFICINALE (ZINGIBERACEAE) ON IMPORTANT PARAMETERS OF LIPID PROFILE.

Investigation of hypolipidimic effects of ginger-juice (ZINGIBER OFFICINALE ROSCOE) in rat. Methods: Albino rats (n=6-12) were administered G.J at single dose (4ml/rat, p.o) as a chronic treatment over period of 21 days. Effect of ginger-juice treatment was studied in rats on the following Lipid profile parameters: 1.Total cholesterol 2. HDL-cholesterol 3. LDL-cholesterol 4. Triglycerides The rats were divided into control and test groups, each group consisting of 6-12 rats. Results: Twenty-one days' treatment with ginger-juice in rats significantly reduced the total serum cholesterol level (136.46 ± 4.06mg/dl of control group to 109.46 ±3.38mg/dl, P<0.001) and significantly increased the serum HDL-cholesterol (41.82 ± 1.32mgldl of control group to 65.42 ± 1.54mg/dl, P<0.001). LDL-cholesterol and triglycerides remained unaltered. It is found that ginger-juice act as hypolipidaemic agent. Conclusion: Ginger-juice reduced the serum total cholesterol whichwas observed rise in normal rats administered ginger-juice over period of twenty-one days.