%0 Journal Article %T TO ESTABLISH THE EFFECT OF GINGER-JUICE ZINGIBER OFFICINALE (ZINGIBERACEAE) ON IMPORTANT PARAMETERS OF LIPID PROFILE. %A S.S.Prasad %A Sushil Kumar %A S.K.Vajpeyee %A V.H. Bhavsar %J International Journal of Pharma Sciences and Research %D 2012 %I KEJA Publications %X Investigation of hypolipidimic effects of ginger-juice (ZINGIBER OFFICINALE ROSCOE) in rat. Methods: Albino rats (n=6-12) were administered G.J at single dose (4ml/rat, p.o) as a chronic treatment over period of 21 days. Effect of ginger-juice treatment was studied in rats on the following Lipid profile parameters: 1.Total cholesterol 2. HDL-cholesterol 3. LDL-cholesterol 4. Triglycerides The rats were divided into control and test groups, each group consisting of 6-12 rats. Results: Twenty-one days' treatment with ginger-juice in rats significantly reduced the total serum cholesterol level (136.46 ¡À 4.06mg/dl of control group to 109.46 ¡À3.38mg/dl, P<0.001) and significantly increased the serum HDL-cholesterol (41.82 ¡À 1.32mgldl of control group to 65.42 ¡À 1.54mg/dl, P<0.001). LDL-cholesterol and triglycerides remained unaltered. It is found that ginger-juice act as hypolipidaemic agent. Conclusion: Ginger-juice reduced the serum total cholesterol whichwas observed rise in normal rats administered ginger-juice over period of twenty-one days. %K Ginger-juice %K Total cholesterol %K HDL-cholesterol %K LDL-cholesterol %K Triglycerides %U http://www.ijpsr.info/docs/IJPSR12-03-04-04.pdf