Application of Modern Immunological Tests and X-Ray Methods in the Diagnosis of Tuberculosis of the Intrathoracic Lymph Nodes in Children

This study helped to ascertain the superiority of Diaskintest (DST) with respect to the wealth of information it provides when compared with the Mantoux test with PPD 2 TU (M2) in determining the activity of tuberculosis infection in children. The evaluation parameters of diagnostic value with DST (DE=77.5%, NPV=72.4%, PPV=91.1%) were significantly higher than with M2x test 2TU (DE=57.2%, NPV=47.6%, PPV=53.2%). On positive testing with Diaskintest , Tuberculosis of Intrathoracic Lymph Nodes (TITLN) showed nodes larger than 0.5 cm, which was determined in 80.4% and could be estimated as minor manifestations of intrathoracic lymphadenopathy against the background of the high activity of tuberculosis infection. Diaskintest and X-ray methods are mandatory in the diagnosis of tuberculosis in children. This is absolutely necessary to adequately assess the child’s condition and provide timely administration of disease specific therapy.