%0 Journal Article
%T Application of Modern Immunological Tests and X-Ray Methods in the Diagnosis of Tuberculosis of the Intrathoracic Lymph Nodes in Children
%A Peter K. Yablonsky
%A PhD
%A ScD1'2
%A Irina F. Dovgalyuk
%A PhD
%A ScD1
%A Anna A. Starshinova
%A PhD1
%A Pavel V. Gavrilov
%A PhD1
%J International Journal of BioMedicine
%D 2012
%I International Medical Research and Development Corporation
%X This study helped to ascertain the superiority of Diaskintest  (DST) with respect to the wealth of information it provides when compared with the Mantoux test with PPD 2 TU (M2) in determining the activity of tuberculosis infection in children. The evaluation parameters of diagnostic value with DST (DE=77.5%, NPV=72.4%, PPV=91.1%) were significantly higher than with M2x test 2TU (DE=57.2%, NPV=47.6%, PPV=53.2%). On positive testing with Diaskintest , Tuberculosis of Intrathoracic Lymph Nodes (TITLN) showed nodes larger than 0.5 cm, which was determined in 80.4% and could be estimated as minor manifestations of intrathoracic lymphadenopathy against the background of the high activity of tuberculosis infection. Diaskintest  and X-ray methods are mandatory in the diagnosis of tuberculosis in children. This is absolutely necessary to adequately assess the childĄ¯s condition and provide timely administration of disease specific therapy.
%K tuberculosis
%K children
%K Diaskintest
%K QuantiFERON-TB test
%K computed tomography
%K diagnostic.
%U http://www.ijbm.org/articles/2_3_PP1.pdf