Determina o da Concentra o Inibitória Mínima do Clotrimazol e da Terbinafina sobre isolados de Candida albicans oriundas da mucosa bucal de pacientes HIV positivos e HIV negativos

Candidiasis is a fungi infection caused by yeasts from Candida genus, that live in the mucosas and justcauses illness when there are favoring conditions to its growth, like immune compromised HIV infected patients.Resistance reports verified in Candida albicans isolates, especially in those immune compromised, and fast andefficient treatment need cause there to be a great interest in studies capable of using in vitro susceptibility tests toadequate therapy choose. The objective of this study was to determine the Minimum Inhibitory Concentration (MIC) ofantifungal agents clotrimazole and terbinafine on 19 isolates of Candida albicans isolated from HIV positive patients and HIV-negative with oral erythematous candidiasis to detect possible resistance. Using agar antifungal dilutionthecnic and sample at demarcated regions on Petri dish. It was verified that MIC to terbinafine varied from 32 to 128μg/mL while to clotrimazole, MIC varied from 16 to 128 μg/mL. This study allowed concluding that almost samplesshowed elevated MIC values among HIV positive or negative patients.