Bioseparations in aqueous two-phase systems

Bioseparations conducted in aqueous two-phase systems offer a great number of advantages over the conventional separation techniques. Among them the most relevant are rapid mass transfer due to low interfacial tension, rapid and selective separation, easiness of operation mode, reliability in scale-up biocompatibility and environment-friendly features, and possibility of process integration when applied in biomolecule production. Upon overcoming the major problem - mostly empirical establishment of operating conditions bioseparations in aqueous two-phase systems will become a necessary step in both existing and newly developed bioprocesses for the primary recovery of products.