Induction of apoptosis by the aqueous and ethanolic leaf extract of Vitex negundo L. in MCF-7 human breast cancer cells

The aim of this investigation was to evaluate the anti-proliferative potential of aqueous andethanolic extract from Vitex negundo against human breast cancer cell (MCF-7). The aqueous and ethanolextract from V. negundo potently inhibited growth of MCF-7 in a concentration-dependent manner. V.negundo pretreatment resulted in deferential cell viability and IC50 value were observed in MCF-7 cell linebut not in control cell line. The above result suggested that V. negundo has a potential benefits in breastcancer cells.