%0 Journal Article
%T Induction of apoptosis by the aqueous and ethanolic leaf extract of Vitex negundo L. in MCF-7 human breast cancer cells
%A Arulvasu C.
%A Prabhu D.
%A Manikandan R.
%A Srinivasan P.
%J International Journal of Drug Discovery
%D 2010
%I 
%X The aim of this investigation was to evaluate the anti-proliferative potential of aqueous andethanolic extract from Vitex negundo against human breast cancer cell (MCF-7). The aqueous and ethanolextract from V. negundo potently inhibited growth of MCF-7 in a concentration-dependent manner. V.negundo pretreatment resulted in deferential cell viability and IC50 value were observed in MCF-7 cell linebut not in control cell line. The above result suggested that V. negundo has a potential benefits in breastcancer cells.
%K Anti-cancer
%K anti-proliferative
%K breast cancer
%K cytotoxicity
%K V. negundo
%K MCF-7
%U http://www.bioinfo.in/uploadfiles/12666459262_1_1_IJDD.pdf