Effect of the Bonding Amounts of Chiral Ligand Exchange Chromatogr-aphic Stationary Phases on the Enantioseparation of Amino Acids
硅胶键合手性配体交换固定相键合量对α-氨基酸拆分的影响

L proline chiral stationary phases with various bonding amounts for ligand exchange chromatography were prepared by treating silica gel with 3 glycidoxypropyltrimethoxysilane and bonding L proline. The bonding amounts of L proline chiral stationary phase were controlled effectively and characterized by IR and elemental analysis. Some DL amino acids were separated and the influences of the bonding amounts on the efficiency of resolution of DL amino acids by ligand exchange chromatography were briefly discussed and explained by the mechanism of the separation.