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色谱  2002 

Advances in the Chiral Resolution of Organophosphorus Compounds by Liquid Chromatography
手性有机磷化合物液相拆分的研究进展

Keywords: liquid chromatography,chiral stationary phase,organophosphorus compound,chiral resolution
液相色谱
,手性固定相,有机磷化合物,手性拆分

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Abstract:

The developments in the chiral resolution of organophosphorus compounds by liquid chromatography in recent years are reviewed. Two different approaches of separation: indirect resolution (chiral derivatization reagent method) and direct resolution (chiral mobile phase additive and chiral stationary phase), focusing on several chiral stationary phases--Pirkle type, cyclodextrin, cellulose, ligand exchange and other chiral stationary phases are presented. The possible mechanism of chiral recognition is discussed. Eighty-five references are involved.

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