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色谱 1995
Optimization of Multl-Column System Selectivity
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Abstract:
nified method using multi-column system is the best way to solve separation problem of complex mix-tures. Multi-column switching and selectivity tuning of serially connected columns are not a desirable waydue to complicated operation an instrumentation. Therefore,an intelligent method of multi-column systemhas been developed. This paper presents some principles and optimization methods of multi-coluun systemselectivity for different cases of sample composition. Optimization of multi-colurnn system for three typicalsamples,mixtures of different classes of compounds,isomers,and enantiomers,is discussed.