Progress on G-quadruplex as targets in anticancer drug structure screening and rational design
基于DNA G-四链体识别的抗肿瘤分子筛选及结构设计研究进展

Based on the recognition of bio-target molecules, screening novel anti-cancer drugs has become one of the research focuses. The revealing of the relationship between the G-quadruplex and cancer by modern molecular biology techniques provides a new opportunity to the anti-cancer drugs research. A general consensus is that organic molecules that induce or stabilize G-quadruplex structures could pave the way for the discovery of novel anti-cancer agents. Therefore, it attracts the interest of chemists and biol...