%0 Journal Article
%T Progress on G-quadruplex as targets in anticancer drug structure screening and rational design<br>基于DNA G-四链体识别的抗肿瘤分子筛选及结构设计研究进展
%A Zhang XiuFeng
%A Xiang JunFeng
%A Tian MingYue
%A Tang YaLin Institute of Chemistry
%A Chinese Academy of Sciences
%A Beijing
%A China
%A College of Life Sciences
%A Beijing Normal University
%A Beijing
%A <br>张秀凤
%A 向俊锋
%A 田明月
%A 唐亚林
%J 科学通报
%D 2009
%I 
%X Based on the recognition of bio-target molecules, screening novel anti-cancer drugs has become one of the research focuses. The revealing of the relationship between the G-quadruplex and cancer by modern molecular biology techniques provides a new opportunity to the anti-cancer drugs research. A general consensus is that organic molecules that induce or stabilize G-quadruplex structures could pave the way for the discovery of novel anti-cancer agents. Therefore, it attracts the interest of chemists and biol...
%K G-quadruplex
%K anticancer drug
%K screening
%K structure design<br>G-四链体
%K 抗肿瘤药物
%K 化合物筛选
%K 结构设计
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=7C7E63796F062382A606A3A9833B8C05&jid=B40D4BA57FF46E45205A09B4DC283152&aid=67C7A9E6FCC525126D9EF99F06AEF5B4&yid=DE12191FBD62783C&vid=318E4CC20AED4940&iid=F3090AE9B60B7ED1&sid=2A46E9718B53247E&eid=2B78D85EBFEED708&journal_id=0023-074X&journal_name=科学通报&referenced_num=0&reference_num=0