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计算机科学 2010
Artificial Gene Regulatory Networks Construction Based on Complex Network
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Abstract:
Along with the explosion of high-throughput genomic information produced from such as DNA microarrays,modeling the mechanism of gene regulations and constructing gene regulatory network become an urgent task.We proposed a novel method,GN-Simulator,to simulate gene regulatory networks based on complex network theory.The real gene networks were modeled explicitly in matrixes based on the scale-free topology.According to the robust biological mechanism,we constructed artificial gene regulatory networks related...