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ISSN: 2333-9721
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Artificial Gene Regulatory Networks Construction Based on Complex Network
基于复杂网络模型的基因调控网络的计算模拟

Keywords: Complex network,Scale-free topology,Dynamic stability,Simulation,Gene regulatory network
复杂网络
,无标度特性,动力学稳定性,模拟,基因调控网络

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Abstract:

Along with the explosion of high-throughput genomic information produced from such as DNA microarrays,modeling the mechanism of gene regulations and constructing gene regulatory network become an urgent task.We proposed a novel method,GN-Simulator,to simulate gene regulatory networks based on complex network theory.The real gene networks were modeled explicitly in matrixes based on the scale-free topology.According to the robust biological mechanism,we constructed artificial gene regulatory networks related...

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