%0 Journal Article %T Artificial Gene Regulatory Networks Construction Based on Complex Network
基于复杂网络模型的基因调控网络的计算模拟 %A ZHANG Lu-wen %A XIE Jiang %A CHEN Jian-jiao %A ZHANG Wu %A
张律文 %A 谢江 %A 陈建娇 %A 张武 %J 计算机科学 %D 2010 %I %X Along with the explosion of high-throughput genomic information produced from such as DNA microarrays,modeling the mechanism of gene regulations and constructing gene regulatory network become an urgent task.We proposed a novel method,GN-Simulator,to simulate gene regulatory networks based on complex network theory.The real gene networks were modeled explicitly in matrixes based on the scale-free topology.According to the robust biological mechanism,we constructed artificial gene regulatory networks related... %K Complex network %K Scale-free topology %K Dynamic stability %K Simulation %K Gene regulatory network
复杂网络 %K 无标度特性 %K 动力学稳定性 %K 模拟 %K 基因调控网络 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=8240383F08CE46C8B05036380D75B607&jid=64A12D73428C8B8DBFB978D04DFEB3C1&aid=A032FC63D02E1C590CAD5A4144D53B59&yid=140ECF96957D60B2&vid=42425781F0B1C26E&iid=CA4FD0336C81A37A&sid=CC0ECB9C52F1B85F&eid=527AEE9F3446633A&journal_id=1002-137X&journal_name=计算机科学&referenced_num=0&reference_num=15