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菌物学报 2011
Protective effects of crude polysaccharides from Chroogomphus rutilus on dopaminergic neurons impaired by MPTP in mice
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Abstract:
To investigate the protective effects of crude polysaccharides from Chroogomphus rutilus on doaminergic neurons impaired by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6J mice were investigated,and to analyse the antioxidant activity of the crude polysaccharides in vitro was analysed. The mouse model of Parkinson's disease was duplicated by using intraperitoneal injection of MPTP. The mice were pretreated through gavage with different dosages of crude polysaccharides (100mg/kg,200mg/kg and ...
