%0 Journal Article
%T Protective effects of crude polysaccharides from Chroogomphus rutilus on dopaminergic neurons impaired by MPTP in mice
色钉菇粗多糖对小鼠DA能神经元MPTP损伤的保护作用
%A ZHANG Xue-Qian
%A SUN Hong
%A WANG Li-An
%A WANG Yan-Qin
%A LIU Chuan
%A BAI Yun
%A LI Jie
%A GUAN Zhen-Long
%A
张雪倩
%A 孙红
%A 王立安
%A 王艳芹
%A 刘川
%A 白云
%A 李洁
%A 管振龙
%J 菌物学报
%D 2011
%I
%X To investigate the protective effects of crude polysaccharides from Chroogomphus rutilus on doaminergic neurons impaired by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6J mice were investigated,and to analyse the antioxidant activity of the crude polysaccharides in vitro was analysed. The mouse model of Parkinson's disease was duplicated by using intraperitoneal injection of MPTP. The mice were pretreated through gavage with different dosages of crude polysaccharides (100mg/kg,200mg/kg and ...
%K Parkinson's disease
%K substantia nigra
%K behavior
%K protective effects
%K antioxidant
帕金森病,黑质,行为,保护作用,抗氧化
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=CA9F815FCB0F62294C4266BB6F902ACB&aid=E48D77FE2A9C1B1D6BC0E2A161579C61&yid=9377ED8094509821&vid=340AC2BF8E7AB4FD&iid=CA4FD0336C81A37A&sid=E44E40A2398D4F2A&eid=656F8C8401D91023&journal_id=1672-6472&journal_name=菌物学报&referenced_num=0&reference_num=62