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Molbank 2009
Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylateDOI: 10.3390/m645 Keywords: Biginelli reaction, solvent-free conditions, microwave irradiation, 3,4-dihydropyrimidin-2(1H)-thione Abstract: Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under solvent-free conditions in high yield and good purity.
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