Advance in the Entire Balance and Local Unbalance of Base Distribution in Genome
基因组内碱基分布整体均衡与局部不均衡的研究进展 Advance in the Entire Balance and Local Unbalance of Base Distribution in Genome

With more and more genome have been completely sequenced, scientists find the Partial Rule 2 (PR2) in entire single strand that A approximately equal to T, G approximately equal to C. But from the scope of thousands to hundreds of thousand bases, A not = T, G not = C. From the view of math, if the mutational rate of one strand is equal to others, it could be proved that A approximately equal to T, G approximately equal to C, but from the view of experience, that premise doesn't exist, so the solution of the problem needs the deeply combination of biology and math.