%0 Journal Article
%T Advance in the Entire Balance and Local Unbalance of Base Distribution in Genome<br>基因组内碱基分布整体均衡与局部不均衡的研究进展 Advance in the Entire Balance and Local Unbalance of Base Distribution in Genome
%A ZHONG Dong
%A ZHAO Gui jun
%A ZHANG Zhen shu
%A XUN An long
%A <br>钟东
%A 赵贵军
%A 张振书
%A 徐安龙
%J 遗传
%D 2002
%I 
%X With more and more genome have been completely sequenced, scientists find the Partial Rule 2 (PR2) in entire single strand that A approximately equal to T, G approximately equal to C. But from the scope of thousands to hundreds of thousand bases, A not = T, G not = C. From the view of math, if the mutational rate of one strand is equal to others, it could be proved that A approximately equal to T, G approximately equal to C, but from the view of experience, that premise doesn't exist, so the solution of the problem needs the deeply combination of biology and math.
%K base distribution
%K genome
%K bioinformatics<br>基因组
%K 碱基分布
%K 整体均衡
%K 局部不均衡
%K 研究进展
%K 生物信息学
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=3AD22BE5DFFC1ACC&yid=C3ACC247184A22C1&vid=B91E8C6D6FE990DB&iid=38B194292C032A66&sid=381FB4265090A8E0&eid=26AEEED215BE97D0&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=52