Analysis of genetic polymorphisms of 10 STR loci on chromosome 11 in a Shaanxi Han population
陕西省汉族人群11号染色体10个STR基因座的遗传多态性研究

D11S1760,D11S4102,D11S4116,D11S4207,D11S4162,D11S914,D11S4127,D11S917,D11S4146 and D11S915 of 10 short tandem repeat(STR) loci on chromosome 11 were analyzed by fluorescence-based gene scan tech-nique to understand the genetic polymorphisms of those STR loci on chromosome 11 in a Han population in Shaanxi pro-vince.The results showed that the number of alleles and genotypes observed at loci D11S1760,D11S4102,D11S4116,D11S4207,D11S4162,D11S914,D11S4127,D11S917,D11S4146 and D11S915 were 17,11,15,11,4,6,7,12,11 and 13 for alleles and 41,18,36,30,8,10,16,30,29 and 32 for genotypes,respectively.All the 10 loci were in Hardy-Weinberg equilibrium.The heterozygosities of each STR locus was 86.72%,67.95%,83.90%,85.96%,58.18%,57.63%,72.60%,72.73%,77.87% and 86.40%.It concluded the 10 loci on chromosome 11 were relatively highly genetic polymorphic in Han populations and could provide useful markers for genetic studies.