%0 Journal Article
%T Analysis of genetic polymorphisms of 10 STR loci on chromosome 11 in a Shaanxi Han population<br>陕西省汉族人群11号染色体10个STR基因座的遗传多态性研究
%A REN Feng-Ling
%A GUO Xiong
%A SHI Xiao-Wei
%A PING Zhi-Guang
%A <br>任峰玲
%A 郭雄
%A 史晓薇
%A 平智广
%J 遗传
%D 2007
%I 
%X D11S1760,D11S4102,D11S4116,D11S4207,D11S4162,D11S914,D11S4127,D11S917,D11S4146 and D11S915 of 10 short tandem repeat(STR) loci on chromosome 11 were analyzed by fluorescence-based gene scan tech-nique to understand the genetic polymorphisms of those STR loci on chromosome 11 in a Han population in Shaanxi pro-vince.The results showed that the number of alleles and genotypes observed at loci D11S1760,D11S4102,D11S4116,D11S4207,D11S4162,D11S914,D11S4127,D11S917,D11S4146 and D11S915 were 17,11,15,11,4,6,7,12,11 and 13 for alleles and 41,18,36,30,8,10,16,30,29 and 32 for genotypes,respectively.All the 10 loci were in Hardy-Weinberg equilibrium.The heterozygosities of each STR locus was 86.72%,67.95%,83.90%,85.96%,58.18%,57.63%,72.60%,72.73%,77.87% and 86.40%.It concluded the 10 loci on chromosome 11 were relatively highly genetic polymorphic in Han populations and could provide useful markers for genetic studies.
%K short tandem repeat
%K genetic polymorphism
%K chromosome 11
%K Hardy-Weinberg equilibrium<br>短串联重复序列
%K 遗传多态性
%K 11号染色体
%K Hardy-Weinberg平衡
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=F4F7599549ED610DC87765B9E43A4C1D&yid=A732AF04DDA03BB3&vid=771469D9D58C34FF&iid=59906B3B2830C2C5&sid=0049ED447A3A3206&eid=E34F1AE8B0BD0598&journal_id=0253-9772&journal_name=遗传&referenced_num=1&reference_num=13