Preparation and in Vitro Drug Release Behavior Study of Porous Phosphate Glass Ceramic
多孔微晶玻璃作为药物载体材料的制备及其体外释药研究

The preparation and properties of porous glass ceramic (PGC) carrier materials made from the base glass composition CaO-P2O5 were investigated. Rifapin (R) was used as a model drug, in vitro drug delivery anylyses of R-PGC were performed. Based on this results, the drug carrier can gradually re1ease rifapin with effective drug concentration in 1ong time. Through the adjustment of aspect ratios of calcium phosphate fiber, the porosity can be effeictely changed. So it is helpful to make the durg delivery system (DDS), and further study should be engaged.