%0 Journal Article %T Preparation and in Vitro Drug Release Behavior Study of Porous Phosphate Glass Ceramic
多孔微晶玻璃作为药物载体材料的制备及其体外释药研究 %A WANG De-Ping %A HUANG Wen-Hai %A CHENG Tian-Dan %A
王德平 %A 黄文旵 %A 陈天丹 %J 无机材料学报 %D 2001 %I Science Press %X The preparation and properties of porous glass ceramic (PGC) carrier materials made from the base glass composition CaO-P2O5 were investigated. Rifapin (R) was used as a model drug, in vitro drug delivery anylyses of R-PGC were performed. Based on this results, the drug carrier can gradually re1ease rifapin with effective drug concentration in 1ong time. Through the adjustment of aspect ratios of calcium phosphate fiber, the porosity can be effeictely changed. So it is helpful to make the durg delivery system (DDS), and further study should be engaged. %K bioglass ceramic %K drug carrier %K slow-release
生物微晶玻璃 %K 药物载体 %K 缓释作用 %K 药物 %K 控释性释放 %K 制备 %K 显微结构 %K 体外释药 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=84529CA2B2E519AC&jid=ABC0063016AF57E1C73EF43C8D2212BD&aid=02CC6087358899C7&yid=14E7EF987E4155E6&vid=7801E6FC5AE9020C&iid=B31275AF3241DB2D&sid=C1F642278C6E9D3E&eid=9978E8308B7F7CE6&journal_id=1000-324X&journal_name=无机材料学报&referenced_num=12&reference_num=5