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amongAnimal-associated Pathogens-a review
群体感应及其在动物病原菌致病中的作用

Keywords: Keywords: quorum sensing,autoinducer,pathogens,virulence factor,biofilm
关键词:
,群体感应,自体诱导物,病原菌,毒力因子,生物膜

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Abstract:

Abstract: Quorum sensing (QS) is a phenomenon that microbes regulate some of their genes by signals related to the density of population. It is confirmed that acyl-homoserine lactones (AHL), some peptides, some furanones and some other small moleculars can be used as quorum-sensing signals by microbes. Microbes control their physiology with different QS systems in parallel or hierarchical ways. A lot of microbial pathogenesis connect with quorum sensing closely. More and more studies show that QS systems regulate in microbial pathogenesis through the following points: (1) QS helping pathogens invasion and colonization; (2) QS regulating production of virulent factor; (3) QS giving pathogens the ability of immunity or drug resistance. We review the role of QS in microbial pathogenesis and address a new way to prevent and control microbial diseases.

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