%0 Journal Article %T amongAnimal-associated Pathogens-a review
群体感应及其在动物病原菌致病中的作用 %A Qingping Wu %A Kui Wu %A Yingwang Ye %A Xiaohui Dong %A Jumei Zhang %A
吴清平 %A 吴葵 %A 叶应旺 %A 董晓晖 %A 张菊梅 %J 微生物学报 %D 2009 %I %X Abstract: Quorum sensing (QS) is a phenomenon that microbes regulate some of their genes by signals related to the density of population. It is confirmed that acyl-homoserine lactones (AHL), some peptides, some furanones and some other small moleculars can be used as quorum-sensing signals by microbes. Microbes control their physiology with different QS systems in parallel or hierarchical ways. A lot of microbial pathogenesis connect with quorum sensing closely. More and more studies show that QS systems regulate in microbial pathogenesis through the following points: (1) QS helping pathogens invasion and colonization; (2) QS regulating production of virulent factor; (3) QS giving pathogens the ability of immunity or drug resistance. We review the role of QS in microbial pathogenesis and address a new way to prevent and control microbial diseases. %K Keywords: quorum sensing %K autoinducer %K pathogens %K virulence factor %K biofilm
关键词: %K 群体感应 %K 自体诱导物 %K 病原菌 %K 毒力因子 %K 生物膜 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=AB8B3C37A7A127EE391019A1E7A6A63C&yid=DE12191FBD62783C&vid=2A3781E88AB1776F&iid=DF92D298D3FF1E6E&sid=970314C3B74F6C4D&eid=9596F7248FB5796B&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=36