%0 Journal Article
%T amongAnimal-associated Pathogens-a review
群体感应及其在动物病原菌致病中的作用
%A Qingping Wu
%A Kui Wu
%A Yingwang Ye
%A Xiaohui Dong
%A Jumei Zhang
%A
吴清平
%A 吴葵
%A 叶应旺
%A 董晓晖
%A 张菊梅
%J 微生物学报
%D 2009
%I
%X Abstract: Quorum sensing (QS) is a phenomenon that microbes regulate some of their genes by signals related to the density of population. It is confirmed that acyl-homoserine lactones (AHL), some peptides, some furanones and some other small moleculars can be used as quorum-sensing signals by microbes. Microbes control their physiology with different QS systems in parallel or hierarchical ways. A lot of microbial pathogenesis connect with quorum sensing closely. More and more studies show that QS systems regulate in microbial pathogenesis through the following points: (1) QS helping pathogens invasion and colonization; (2) QS regulating production of virulent factor; (3) QS giving pathogens the ability of immunity or drug resistance. We review the role of QS in microbial pathogenesis and address a new way to prevent and control microbial diseases.
%K Keywords: quorum sensing
%K autoinducer
%K pathogens
%K virulence factor
%K biofilm
关键词:
%K 群体感应
%K 自体诱导物
%K 病原菌
%K 毒力因子
%K 生物膜
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=AB8B3C37A7A127EE391019A1E7A6A63C&yid=DE12191FBD62783C&vid=2A3781E88AB1776F&iid=DF92D298D3FF1E6E&sid=970314C3B74F6C4D&eid=9596F7248FB5796B&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=36