Study of Screening Effective Components of Jiaweisimiaowan
加味四妙丸有效部位群的筛选研究

To study the material foundation of the effectiveness of Jiaweisimiaowan, a Chinese patent drug for arthrolithiasis, determine the functions of its effectiveness and trace its components. Method: To separate and purify the components of the said patent drug, e. i., alkalord, saponin, flavore, organic acid, volatile oil and water and screen and determine its effective components for anti - inflammation and analgesia by taking for indexes the results of the anti -inflammatory experiment of mice's ears with dimethylbenzene, the analgesia experiment by stimulating mice with acetic acid and the experiment of reducing the activity of uric acid in a hyperuric model, and identify the group of effective components of the drug and its functions on the targets of effectiveness through perpendicularly combined screening of all the effective components. Result: The functions of anti - inflammation, analgesia and the reduction of the activity of uric acid of the 6 combined components are in accord with those of the said patent drug and thus the 6 ones make up the group of effective components of it. Volatile oil plays the major role in anti - inflammation, analgesia and the reduction of the activity of uric acid through the combination and compatibility of all the components.