%0 Journal Article
%T Study of Screening Effective Components of Jiaweisimiaowan
加味四妙丸有效部位群的筛选研究
%A Yin Lian
%A Xu Li
%A Shi Le
%A Wu Hao
%A
尹莲
%A 徐立
%A 时乐
%A 吴皓
%J 世界科学技术-中医药现代化
%D 2005
%I
%X To study the material foundation of the effectiveness of Jiaweisimiaowan, a Chinese patent drug for arthrolithiasis, determine the functions of its effectiveness and trace its components. Method: To separate and purify the components of the said patent drug, e. i., alkalord, saponin, flavore, organic acid, volatile oil and water and screen and determine its effective components for anti - inflammation and analgesia by taking for indexes the results of the anti -inflammatory experiment of mice's ears with dimethylbenzene, the analgesia experiment by stimulating mice with acetic acid and the experiment of reducing the activity of uric acid in a hyperuric model, and identify the group of effective components of the drug and its functions on the targets of effectiveness through perpendicularly combined screening of all the effective components. Result: The functions of anti - inflammation, analgesia and the reduction of the activity of uric acid of the 6 combined components are in accord with those of the said patent drug and thus the 6 ones make up the group of effective components of it. Volatile oil plays the major role in anti - inflammation, analgesia and the reduction of the activity of uric acid through the combination and compatibility of all the components.
%K Jiaweisimiaowan
%K effective components
%K anti-inflammation
%K analgesia
%K reduction of uric acid
加味回妙丸
%K 有效部位
%K 筛选
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=B5F35A1FC27C1FF7&jid=44257A35316DB0727BA6BC707B9EDAAB&aid=29C0764AAC1C331F1ECF5F2F3404D154&yid=2DD7160C83D0ACED&vid=DF92D298D3FF1E6E&iid=E158A972A605785F&sid=D3E34374A0D77D7F&eid=B73CD265D730D76FCDF5FE606671E968&journal_id=1674-3849&journal_name=世界科学技术-中医药现代化&referenced_num=1&reference_num=0