RECENT ADVANCES OF P2X RECEPTORS
P2X受体研究进展

The P2X receptors comprise a family of ligand-gated cation channels (permeable to both Na + and Ca 2+ ) which are opened by the binding of extracellular ATP. Seven different genes encoding P2X receptors have been cloned, termed P2X 1 to P2X 7 . Native P2X receptors can function as both homo- and hetero- polymers. The structure, distribution, function, biophysical characteristics of P2X receptors to the recent work were described.