A COMPUTER SIMULATION SYSTEM OF DNA-BINDING PROTEIN EXPERIMENT BASED ON dsDNA MICROARRAY
dsDNA芯片的DNA结合蛋白质计算机模拟系统

DsDNA(double-stranded DNA) microarray, as a novel high-throughout technique, get a start in the field of DNA-binding protein research. It studied a dsDNA probe designing method for a new fabrication technology of the dsDNA microarray. Then a computer software named 'DBP' was intro-duced, which simulated the procedures of DNA-binding protein experiment based on dsDNA microarray and included DNA digestion using restriction enzymes, electrophoresis, hybridization and data manage-ment. Using DBP software, it can design dsDNA probes give advice on experiment planning and predic-tive results of a DNA-binding protein experiment.