%0 Journal Article
%T A COMPUTER SIMULATION SYSTEM OF DNA-BINDING PROTEIN EXPERIMENT BASED ON dsDNA MICROARRAY<br>dsDNA芯片的DNA结合蛋白质计算机模拟系统
%A XIE Jian-ming
%A BAI Yun-fei
%A QIAN Lu-lu
%A CUI Lei
%A SUN Xiao
%A LU Zu-hong
%A <br>谢建明
%A 白云飞
%A 钱璐璐
%A 崔磊
%A 孙啸
%A 陆祖宏
%J 生物物理学报
%D 2003
%I 
%X DsDNA(double-stranded DNA) microarray, as a novel high-throughout technique, get a start in the field of DNA-binding protein research. It studied a dsDNA probe designing method for a new fabrication technology of the dsDNA microarray. Then a computer software named 'DBP' was intro-duced, which simulated the procedures of DNA-binding protein experiment based on dsDNA microarray and included DNA digestion using restriction enzymes, electrophoresis, hybridization and data manage-ment. Using DBP software, it can design dsDNA probes give advice on experiment planning and predic-tive results of a DNA-binding protein experiment.
%K dsDNA
%K microarray
%K DNA
%K binding
%K protein
%K Probe
%K design
%K Computer
%K simulation
%K Bioinformatics<br>dsDNA芯片
%K DNA结合蛋白质
%K 计算机模拟系统
%K 探针设计
%K 生物信息学
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=4755F5B55D7F8BC1&yid=D43C4A19B2EE3C0A&vid=2A8D03AD8076A2E3&iid=0B39A22176CE99FB&sid=3F0AF5EDBC960DB0&eid=1B97AE5098AEB49C&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=13