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生物物理学报 2001
PRINCIPLE AND PERSPECTIVE OF NEUROINFORMATICS
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Abstract:
Neuroinformatics is a frontier and multi-discipline which combines the brain science, the information science and computer science together to investigate the form of neural information carrier, the mechanisms of generation, transmission, processing, coding, storage and retrieving of the neural information, and to construct the data bank system of neuroscience. Neuroinformatics can be subdivided into two parts: the molecular neuroinformatics and the systematic neuroinformatics. A dual coding theory of neuroinformatics was suggested that the neuroinformation coding includes two forms: the digital coding of neuronic impulse sequence and the weighting coding of the synaptic connection. A perspective was made on the tendency and new advancements of neuroinformatics in the 21 century and the Human Neurome Project (HuNP) was also suggested. Human Neurome Project is aimed to measure the position, size, neuron number and density, neuronic branches, connections and synapses, neurotransmitters and receptors, ion channels, function, etc, of the complex structures in the human brain. The necessity and feasibility of the Human Neurome Project and the construction of neural data bank were discussed. Relationship between Human Neurome Project and the Human Brain Project was also analyzed and discussed.