NMR IN COMBINATION WITH AN ANIONIC PARAMAGNETIC SHIFT REAGENT(SR) HAS BEEN USED TO STUDY EXTRACELLULAR AND EXTRACELLULAR CATION CONCENTRATIONS
一种直接观测完整细胞内外钠离子浓度的NMR技术

NMR in combination with an anionic paramagnetic shift reagent ( SR) has been used to study intracellular and extracellular cation concentrations. It is a new developing technique recently. The SR has made it possible to observe the intra- and extracellular Na+ and K+. NMR has the advantages over conventional techniques such as flame photometry and radioisotope tracer of being nondestructive, noninvasive and continuous, so that net fluxes can be followed with a reasonably fast time resolution concentrations. Avoiding possible artifacts of the isolation precedures. We have got some primary results in RBC by NMR with shift reagent.