Express？o do P16 e do PDGFR-Beta no adenocarcinoma gástrico

objectives: to detect immunohistochemistry expression of p16 and pdgfr-beta on gastric adenocarcinoma. methods: thirty six patients submitted to surgery for gastric adenocarcinoma between 1998 and 2002 at santa casa de porto alegre hospital have been studied. variables investigated were: age, gender, tumour size and localization, number of dissected and metastatic nodes, histological type, surgical resection extension and pathological staging. results: no expression of pdgfr-beta has been detected on surgical specimens. concerning to p16, loss of expression lower than 10% and 1% has been detected respectively on 89% and 79% of the specimens studied. conclusion: there has been no correlation among p16 loss and variables studied.