%0 Journal Article
%T Express£¿o do P16 e do PDGFR-Beta no adenocarcinoma g¨¢strico
%A Pinto
%A Rodrigo Pozza
%A Lima
%A Fernando Krebs Cirne
%A Kulkzynski
%A Jane M U
%A Moreira
%A Luis Fernando
%J Revista do Col¨¦gio Brasileiro de Cirurgi£¿es
%D 2009
%I Col¨¦gio Brasileiro de Cirurgi?es
%R 10.1590/S0100-69912009000300004
%X objectives: to detect immunohistochemistry expression of p16 and pdgfr-beta on gastric adenocarcinoma. methods: thirty six patients submitted to surgery for gastric adenocarcinoma between 1998 and 2002 at santa casa de porto alegre hospital have been studied. variables investigated were: age, gender, tumour size and localization, number of dissected and metastatic nodes, histological type, surgical resection extension and pathological staging. results: no expression of pdgfr-beta has been detected on surgical specimens. concerning to p16, loss of expression lower than 10% and 1% has been detected respectively on 89% and 79% of the specimens studied. conclusion: there has been no correlation among p16 loss and variables studied.
%K genes
%K p16
%K receptor
%K platelet-derived growth factor beta
%K adenocarcinoma.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-69912009000300004&lng=en&nrm=iso&tlng=en