Dise？os de investigación en epidemiología genética

this article describes the features of the epidemiologic research designs most commonly used in genetic association studies. case-control studies are efficient in evaluating associations between candidate genes and disease. cohort studies, in contrast, yield a greater degree of causality but are not efficient for the initial exploration to identify gene-disease associations. cross-sectional studies are less expensive, require less time, and are useful for estimating the prevalence of diseases, risk factors, and genetic variants. family-based studies have been successful in finding alleles that confer greater risk for developing mendelian inheritance disorders.