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Resistencia a antibióticos en cepas de Acinetobacter baumannii aisladas de enero a marzo del 2010 en el Hospital Clinicoquirúrgico "Hermanos Ameijeiras"

Keywords: resistance, multi-resistance, acinetobacter baumannii.

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Abstract:

introduction: the infections due to acinetobacter baumannii have increased in past years in patients admitted in intensive care units leading to an increase of resistance to antibiotics and of hospital costs, a greater hospital morbidity and mortality. methods: all strains of acinetobacter baumanni isolated from january to march, 2010 were studied, identified according to the compact vitek 2 automated system methodology, following the recommendations of manufacturer (biomérieux, francia) with id gn cards, the sensitivity tests were carried out with ast n82 cards with automated reading. results: acinetobacter baumanni was isolated in 40 patients. the 77 % correspond to strains isolated from blood. we achieve high percentages of resistance to all beta-lactamase antibiotics even with beta-lactamase inhibitors, the resistance was of 100 % to ampicillin, of 98.6 % to ticarcillin-clavulanic acid and of 66.7 % to ticarcillin-tazobactan. in the interval of 8 years has been an increase of 82 % of resistance to imipenem as well as with the meropenem. there was a 100 % of sensitivity to colistine and tigecicline. conclusions: the strains showed high levels of resistance, mainly to beta-lactamase antibiotics including the carbapenemic5 ones. the resistance to aminoglycosides and quinolones was very high; however, the colistine and the tigecicline remain with a 100 % of sensitivity. the leading mechanism of resistance founded was the presence of carbapenemase, which is a great clinical, microbiological and epidemiological challenge in assistance activity.

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